SCHEMBL3457991

SCHEMBL3457991

C=C(C#N)C(=O)OCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
ALDH1A1 P00352 2/20 0.61
NAAA Q02083 1/20 0.48
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
EPHX1 P07099 1/20 0.46
HCAR2 Q8TDS4 1/20 0.42
FAAH O00519 1/20 0.41
LMNA P02545 1/20 0.41
ACHE P22303 6/20 0.41
DGKA P23743 1/20 0.40
HTR2C P28335 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380049 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL379519 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL15229291 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL719001 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
Ocrylate SCHEMBL29891 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL2903638 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL29340 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL35540 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL973728 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL7744948 1.00 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO claimed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP claimed
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
US-20240240064-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2024-07-18 US claimed
EP-4334368-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2024-03-13 EP claimed
CN-117377706-A Two-part curable composition 博斯蒂克股份公司 2024-01-09 CN claimed
EP-4274628-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS Adhezion Biomedical, LLC (US) 2023-11-15 EP claimed
CN-117062636-A Catheter securement compositions and methods 艾德合森生物医药有限责任公司 2023-11-14 CN claimed
WO-2022150498-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS ADHEZION BIOMEDICAL, LLC (US) 2022-07-14 WO claimed
US-20220218951-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS PROVIDING SIGNIFICANTLY STRONG SECUREMENT, WATER RESISTANT SEAL, EFFECTIVE HEMOSTATIS, AND ANTIBACTERIAL PROPERTIES AT AND AROUND VASCULAR ACCESS SITES H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2022-07-14 US claimed
WO-2013129722-A1 TISSUE ADHESIVE FOR WOUND CLOSURE AND PREPARATION METHOD THEREOF GENEWEL CO., LTD (KR) 2013-09-06 WO claimed
US-20100112036-A1 Cyanoacrylate-based liquid microbial sealant drape ADHEZION BIOMEDICAL, LLC. (US) 2010-05-06 US claimed
WO-2010051445-A2 CYANOACRYLATE-BASED LIQUID MICROBIAL SEALANT DRAPE ADHEZION BIOMEDICAL, LLC. (US) 2010-05-06 WO claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 EP claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF TSHR 148/4885ALDH1A1 3677/4885NAAA 931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.