SCHEMBL29026474

C#C[C@]1(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)O[C@@H](n2ccc(=O)[nH]c2=O)[C@@H](F)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	DUT	P33316	4/20	0.38

▸	NT5E	P21589	2/20	0.38

▸	SMYD2	Q9NRG4	2/20	0.31

▸	P2RY14	Q15391	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18460935	0.88	DUT (0.40)	DUTNT5ESMYD2P2RY14
SCHEMBL16374075	0.88	DUT (0.40)	DUTNT5ESMYD2P2RY14
SCHEMBL29026470	0.85	NT5E (0.32)	NT5E
SCHEMBL16906838	0.85	DUT (0.38)	DUTNT5ESMYD2P2RY14
SCHEMBL29026476	0.85	DUT (0.38)	DUTNT5ESMYD2P2RY14
SCHEMBL18460934	0.85	DUT (0.38)	DUTNT5ESMYD2P2RY14
SCHEMBL15075485	0.84	DUT (0.38)	DUTNT5ESMYD2P2RY14
SCHEMBL29026465	0.83	DUT (0.37)	DUTNT5ESMYD2
SCHEMBL13575513	0.81	DUT (0.45)	DUTNT5EP2RY14
SCHEMBL21125047	0.80	DUT (0.44)	DUTNT5EP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114288313-B	Application of pyrimidine nucleoside medicine in preparing medicine for preventing or treating coronavirus infectious diseases	常晓宇	2023-07-04	—	—	CN	disclosed