Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.59 |
| ▸ | NPC1 | O15118 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25165415 | 0.90 | RAB9A (0.59) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL19961704 | 0.90 | RAB9A (0.59) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL29386742 | 0.90 | RAB9A (0.59) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL26744918 | 0.88 | NPC1 (0.45) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL10297868 | 0.86 | NPC1 (0.76) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL26500221 | 0.83 | APP (0.45) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL5148513 | 0.82 | APP (0.57) | APPCYP19A1 | |
| SCHEMBL27651550 | 0.82 | APP (0.57) | APPCYP19A1 | |
| SCHEMBL25165379 | 0.82 | RAB9A (0.54) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL26745365 | 0.80 | RAB9A (0.63) | RAB9ANPC1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |