SCHEMBL29028016

SCHEMBL29028016

CC(C)(C)OC(=O)N(C(=O)O)C(C)(C)Cc1ccc(Br)c(C(F)F)n1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.34
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28379002 0.75 AKT1 (0.36) SSTR4NPSR1
SCHEMBL28503221 0.74 XPO1 (0.40)
SCHEMBL24102996 0.74 SSTR4 (0.38) SSTR4
SCHEMBL29027712 0.73 KDM4E (0.31)
SCHEMBL20678331 0.68 SSTR4 (0.33) SSTR4
SCHEMBL29024380 0.68
SCHEMBL30420991 0.67 GSK3B (0.36)
SCHEMBL24102998 0.67 GSK3B (0.36)
SCHEMBL17755394 0.66 SSTR4 (0.35) SSTR4
SCHEMBL29601574 0.66 SSTR4 (0.35) SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209664-A Small molecule modulators of IL-17 利奥制药有限公司 2023-06-02 CN disclosed