Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028213 | 1.00 | TP53 (0.44) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| Hydrochloric Acid SCHEMBL29027915 | 0.98 | TP53 (0.43) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| Hydrochloric Acid SCHEMBL29027920 | 0.98 | TP53 (0.43) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL24103297 | 0.90 | THRB (0.37) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL26942612 | 0.90 | THRB (0.37) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| Hydrochloric Acid SCHEMBL30282483 | 0.88 | THRB (0.36) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL27818841 | 0.85 | TP53 (0.44) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL13150879 | 0.83 | TP53 (0.43) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL13150839 | 0.83 | TP53 (0.43) | TP53ALDH1A1NPSR1THRBSLC6A3 | |
| SCHEMBL27797952 | 0.82 | THRB (0.42) | TP53ALDH1A1NPSR1THRBSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317962-A | Imidazopyridazine IL-17 inhibitor compounds | 詹森药业有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116209664-A | Small molecule modulators of IL-17 | 利奥制药有限公司 | 2023-06-02 | — | — | CN | disclosed |