SCHEMBL29028360

SCHEMBL29028360

CCOCCN(C(=O)c1ccc(F)cc1)c1cccc(C(=O)O)c1F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.35
NAMPT P43490 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.34
RAB9A P51151 1/20 0.34
GRM1 Q13255 2/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
NR1I2 O75469 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29028585 0.93 TSHR (0.39) KDM4ETSHRLMNANAMPTKMT2A
SCHEMBL29028446 0.92 NR1I2 (0.40) KDM4ETSHRKMT2AMEN1GRM1
SCHEMBL31679335 0.91 KDM4E (0.39) KDM4ETSHRLMNANAMPTKMT2A
SCHEMBL29028498 0.89 CYP1A2 (0.41) KDM4ETSHRLMNANAMPTKMT2A
SCHEMBL29028340 0.88 KDM4E (0.41) KDM4ETSHRNAMPTKMT2AMEN1
SCHEMBL29028363 0.88 KMT2A (0.41) KDM4ENAMPTKMT2AMEN1RAB9A
SCHEMBL29028410 0.81 KMT2A (0.43) KDM4ETSHRKMT2AMEN1LTB4R2
SCHEMBL1807673 0.79 TSHR (0.43) TSHRGRM1LTB4R2MAPT
SCHEMBL29028657 0.78 CYP2C19 (0.46) KDM4ETSHRLMNANAMPTKMT2A
SCHEMBL29028365 0.77 KMT2A (0.42) KDM4EKMT2AMEN1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4610251-A1 HEPTAFLUOROISOPROPYL-CONTAINING BISAMIDE COMPOUND AND INTERMEDIATE COMPOUND THEREOF, AND PREPARATION METHODS THEREFOR AND USE THEREOF Zhejiang Udragon Pesticides And Chemicals Co., Ltd. (CN) 2025-09-03 EP disclosed
CN-115974717-B Bisamide compound containing sevoflurane isopropyl and intermediate compound thereof, preparation method and application thereof 浙江宇龙药业有限公司 2025-03-14 CN disclosed
CN-115974717-A Heptafluoroisopropyl-containing bisamide compound and intermediate compound thereof, and preparation method and application thereof 浙江宇龙药业有限公司 2023-04-18 CN disclosed