Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.91 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.46 |
| ▸ | PRKCB | P05771 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | PRKCH | P24723 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 2/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL2110033 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2902499 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2111697 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL8767287 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2110750 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2109879 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2111711 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2110067 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL8766490 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 | |
| Methyl Alcohol SCHEMBL2111445 | 1.00 | ALDH1A1 (0.91) | ALDH1A1EPHX1TDP1SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725902-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-05-07 | — | — | EP | disclosed |
| WO-2012139028-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
| CN-101820757-A | Treatment of viral infections by modulation of host cell metabolic pathways | UNIV PRINCETON | 2010-09-01 | — | — | CN | disclosed |
| EP-2166843-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009023059-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-02-19 | — | — | WO | disclosed |
| US-6153589-A | FOR TREATING VIRAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0454463-B1 | Process for producing epoxyalcohols of high optical purity | ARCO CHEM TECH (US) | 1997-08-13 | — | — | EP | disclosed |
| EP-0422897-B1 | Recovery of water-insoluble epoxy alcohols | ARCO CHEM TECH (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5278070-A | Process for producing epoxyalcohols of high optical purity | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-01-11 | — | — | US | disclosed |
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0454463-A2 | Process for producing epoxyalcohols of high optical purity | ARCO Chemical Technology, L.P. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0422897-A2 | Recovery of water-insoluble epoxy alcohols | ARCO Chemical Technology, L.P. (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4935101-A | Process for the recovery of a water-insoluble epoxy alcohol | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1990-06-19 | — | — | US | disclosed |