SCHEMBL29028645

SCHEMBL29028645

Brc1ccc(N(c2ccccc2)c2cccc(-c3ccccc3-c3ccccc3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
MAPK1 P28482 3/20 0.42
CYP1A2 P05177 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGES O14684 1/20 0.35
HTT P42858 1/20 0.34
CSF1R P07333 2/20 0.33
CDK2 P24941 2/20 0.33
MARK3 P27448 2/20 0.33
CSNK2A1 P68400 2/20 0.33
MARK2 Q7KZI7 2/20 0.33
AURKB Q96GD4 2/20 0.33
PLK4 O00444 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30512156 0.89 ALDH1A1 (0.54) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL19998701 0.89 ALDH1A1 (0.41) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL19429290 0.88 NPC1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL22078975 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL22079691 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL22079661 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL30481490 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL22078976 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL17402575 0.87 ALDH1A1 (0.52) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1
SCHEMBL1324131 0.87 BACE1 (0.41) ALDH1A1MAPK1CYP1A2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110024155-B Organic light emitting device 株式会社LG化学 2023-07-04 CN disclosed