Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553007 | 0.86 | ESR2 (0.66) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL11901421 | 0.83 | ESR2 (0.50) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL28748627 | 0.83 | MEN1 (0.59) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL28748687 | 0.80 | NPC1 (0.62) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL23320550 | 0.79 | NPC1 (0.57) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL15910787 | 0.79 | MAPT (0.57) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL5077845 | 0.79 | MEN1 (0.57) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL14036890 | 0.79 | ESR2 (0.47) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL29602757 | 0.78 | ADORA3 (0.57) | NPC1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL28748705 | 0.78 | ADORA3 (0.57) | NPC1LMNAMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184598-A | Photocatalytic preparation method and application of N- (2-phenyl-2H-indazole-3-yl) benzamide compound | 河南师范大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115385858-A | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-formamide compound | 河南师范大学 | 2022-11-25 | — | — | CN | disclosed |