Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | ATF1 | P18846 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060089 | 0.80 | RXFP1 (0.44) | HPGDALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL18668464 | 0.77 | KDM4E (0.44) | HPGDALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL29489803 | 0.77 | KDM4E (0.44) | HPGDALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL21559919 | 0.75 | CYP1A2 (0.57) | HPGDL3MBTL1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL5236509 | 0.74 | SMN1; SMN2 (0.50) | HPGDL3MBTL1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL17941430 | 0.72 | NOTUM (0.43) | L3MBTL1ALDH1A1LMNANPSR1GAA | |
| SCHEMBL29679554 | 0.72 | NOTUM (0.43) | L3MBTL1ALDH1A1LMNANPSR1GAA | |
| SCHEMBL30481800 | 0.72 | AGBL2 (0.50) | HPGDL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16389694 | 0.72 | AGBL2 (0.50) | HPGDL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20580213 | 0.71 | PTGER4 (0.47) | HPGDL3MBTL1ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |