Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19760186 | 1.00 | RCE1 (0.46) | RCE1HTTTSHRALDH1A1LMNA | |
| SCHEMBL19758116 | 1.00 | RCE1 (0.46) | RCE1HTTTSHRALDH1A1LMNA | |
| SCHEMBL17892932 | 0.91 | RCE1 (0.44) | RCE1HTTTSHRALDH1A1LMNA | |
| SCHEMBL9497428 | 0.87 | RCE1 (0.41) | RCE1HTTTSHRSLC1A3SLC1A2 | |
| SCHEMBL9577156 | 0.87 | RCE1 (0.41) | RCE1HTTTSHRSLC1A3SLC1A2 | |
| SCHEMBL16176950 | 0.87 | RCE1 (0.41) | RCE1TSHRMAPTSLC1A3SLC1A2 | |
| SCHEMBL19760189 | 0.87 | RCE1 (0.41) | RCE1TSHRMAPTSLC1A3SLC1A2 | |
| SCHEMBL20743832 | 0.87 | RCE1 (0.41) | RCE1TSHRMAPTSLC1A3SLC1A2 | |
| SCHEMBL8672156 | 0.83 | RCE1 (0.39) | RCE1HTTTSHRMAPTSLC1A3 | |
| SCHEMBL8672157 | 0.83 | RCE1 (0.39) | RCE1HTTTSHRMAPTSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |