SCHEMBL9497428

SCHEMBL9497428

C=CC[C@@H](OCc1ccccc1)[C@H](O)[C@@H](O)[C@@H](CC=C)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RCE1 Q9Y256 1/20 0.41
SLC1A3 P43003 2/20 0.39
SLC1A2 P43004 2/20 0.39
SLC1A1 P43005 2/20 0.39
CYP2C19 P33261 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
KMT2A Q03164 1/20 0.39
CA1 P00915 3/20 0.38
TSHR P16473 2/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
HTT P42858 1/20 0.36
BCHE P06276 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577156 1.00 RCE1 (0.41) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL29028880 0.87 RCE1 (0.46) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL19760186 0.87 RCE1 (0.46) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL19758116 0.87 RCE1 (0.46) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL8672156 0.85 RCE1 (0.39) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL8672157 0.85 RCE1 (0.39) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL17892932 0.84 RCE1 (0.44) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL31556087 0.83 CA1 (0.46) RCE1SLC1A1KMT2ACA1TSHR
SCHEMBL16176950 0.83 RCE1 (0.41) RCE1SLC1A3SLC1A2SLC1A1CYP2C19
SCHEMBL20743832 0.83 RCE1 (0.41) RCE1SLC1A3SLC1A2SLC1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5220074-A Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same DAISO CO., LTD. (JP) 1993-06-15 US disclosed
US-5210201-A Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same DAISO CO., LTD. (JP) 1993-05-11 US disclosed
US-5198588-A OPTICALLY ACTIVE ISOXAZOLE DERIVATIVES AND INTERMEDIATES FOR PREPARATION THEREOF DAISO CO., LTD. (JP) 1993-03-30 US disclosed
EP-0439129-A2 Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same Daiso Co., Ltd. (JP) 1991-07-31 EP disclosed