Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145684 | 0.83 | PTGDR2 (0.57) | PTGDR2ALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL9121402 | 0.83 | PTGDR2 (0.67) | PTGDR2MAPK1ALDH1A1NPC1LMNA | |
| SCHEMBL14097989 | 0.82 | PTGDR2 (0.49) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6410232 | 0.80 | PTGDR2 (0.63) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13455069 | 0.80 | PTGDR2 (0.63) | PTGDR2MAPK1ALDH1A1NPC1LMNA | |
| SCHEMBL16959585 | 0.79 | PTGDR2 (0.53) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6408845 | 0.79 | PTGDR2 (0.53) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3372357 | 0.79 | PTGDR2 (0.53) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1849118 | 0.78 | MAPK1 (0.52) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3484951 | 0.78 | PTGDR2 (0.44) | PTGDR2MAPK1ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661387-B | Composition for treating pulmonary fibrosis | 维克图斯生物系统有限公司 | 2023-05-30 | — | — | CN | disclosed |