Imidazole

Imidazole

SCHEMBL29029530

[Ru].c1c[nH]cn1.c1ccc(-c2cccnc2-c2ccccn2)nc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
FKBP5 Q13451 1/20 0.39
KDM4E B2RXH2 5/20 0.38
LMNA P02545 3/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
METAP1 P53582 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38
P4HTM Q9NXG6 1/20 0.38
IDO1 P14902 1/20 0.38
PRKCI P41743 1/20 0.38
CYP2A6 P11509 1/20 0.37
TGFBR1 P36897 2/20 0.36
LRRK2 Q5S007 1/20 0.36
HTR7 P34969 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL28676934 0.98 ALDH1A1 (0.41) ALDH1A1FKBP5KDM4ELMNACCR1
Imidazole SCHEMBL28672700 0.97 ALDH1A1 (0.39) ALDH1A1FKBP5KDM4ELMNACCR1
Dipyridyl SCHEMBL3491432 0.84 KDM4E (0.56) ALDH1A1FKBP5KDM4ELMNACCR1
SCHEMBL319436 0.83 KDM4E (0.54) ALDH1A1KDM4ELMNACCR1CCR5
SCHEMBL30561749 0.83 KDM4E (0.54) ALDH1A1KDM4ELMNACCR1CCR5
SCHEMBL78140 0.83 KDM4E (0.54) ALDH1A1KDM4ELMNACCR1CCR5
SCHEMBL1504323 0.83 KDM4E (0.54) ALDH1A1KDM4ELMNACCR1CCR5
Dipyridyl SCHEMBL7143241 0.82 KDM4E (0.58) ALDH1A1FKBP5KDM4ELMNACCR1
SCHEMBL31267547 0.82 KDM4E (0.52) ALDH1A1KDM4ELMNACCR1CCR5
SCHEMBL30984373 0.82 KDM4E (0.52) ALDH1A1KDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217550-A Imidazole terpyridine ruthenium complex dissolved oxygen detection probe and preparation method and application thereof 上海前瞻创新研究院有限公司 2023-06-06 CN claimed
CN-116217550-A Imidazole terpyridine ruthenium complex dissolved oxygen detection probe and preparation method and application thereof 上海前瞻创新研究院有限公司 2023-06-06 CN disclosed
CN-116217550-A Imidazole terpyridine ruthenium complex dissolved oxygen detection probe and preparation method and application thereof 上海前瞻创新研究院有限公司 2023-06-06 CN disclosed