Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491376 | 0.82 | MEN1 (0.46) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL722641 | 0.81 | HTT (0.53) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL14519865 | 0.81 | PPARG (0.55) | ALDH1A1TSHRPKMNPSR1KMT2A | |
| SCHEMBL29501710 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL17208244 | 0.78 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL23844975 | 0.77 | KDM4E (0.50) | ALDH1A1TSHRKMT2AKDM4ELMNA | |
| SCHEMBL29029886 | 0.77 | MEN1 (0.40) | ALDH1A1TSHRCYP1A2CYP2D6KMT2A | |
| SCHEMBL17058837 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2KMT2AIRAK4 | |
| SCHEMBL19383017 | 0.77 | CYP1A2 (0.43) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL9667255 | 0.77 | CYP1A2 (0.41) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028816-B | Synthesis method of substituted isoindoline | 江阴迈康升华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112028816-A | Synthesis method of substituted isoindoline | 江阴迈康升华医药科技有限公司 | 2020-12-04 | — | — | CN | disclosed |