Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639750 | 0.85 | KIT (0.46) | MEN1KMT2AALKGPR119TRPV1 | |
| SCHEMBL2366237 | 0.85 | MAPT (0.47) | DDB1CRBNMEN1KMT2AGPR119 | |
| SCHEMBL2365849 | 0.85 | DDB1 (0.47) | DDB1CRBNGPR119KITCKS1B | |
| SCHEMBL31410432 | 0.84 | KMT2A (0.57) | MEN1KMT2AGPR119TRPV1KIT | |
| SCHEMBL31410416 | 0.84 | KMT2A (0.57) | MEN1KMT2AGPR119TRPV1KIT | |
| SCHEMBL29631768 | 0.84 | HSD11B1 (0.44) | MEN1KMT2ATRPV1GAA | |
| SCHEMBL31651962 | 0.83 | TLR9 (0.50) | DDB1CRBNMEN1KMT2AALK | |
| SCHEMBL31142996 | 0.83 | KIT (0.46) | MEN1KMT2AALKGPR119TRPV1 | |
| SCHEMBL30394316 | 0.83 | MEN1 (0.46) | MEN1KMT2AALKGPR119TRPV1 | |
| SCHEMBL2416854 | 0.83 | MEN1 (0.46) | MEN1KMT2AALKGPR119TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |