Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467691 | 0.87 | GPR119 (0.54) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL29029921 | 0.86 | GPR119 (0.53) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL24964189 | 0.85 | GPR119 (0.61) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL24467884 | 0.83 | GPR119 (0.55) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL5467171 | 0.82 | GPR119 (0.65) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL594427 | 0.82 | GPR119 (0.60) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL24467752 | 0.81 | GPR119 (0.56) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL29165899 | 0.81 | GPR119 (0.57) | GPR119MAPTPTPN11DDB1CRBN | |
| SCHEMBL1447940 | 0.80 | GPR119 (0.65) | GPR119MAPTPTPN11CKS1BSKP1 | |
| SCHEMBL24964179 | 0.80 | GPR119 (0.61) | GPR119MAPTPTPN11CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |