Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | RET | P07949 | 6/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278996 | 0.86 | NR1H2 (0.58) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL2366237 | 0.84 | MAPT (0.47) | GPR119RETDDB1CRBN | |
| SCHEMBL2365849 | 0.84 | DDB1 (0.47) | NR1H2NR1H3GPR119DDB1CRBN | |
| SCHEMBL14686506 | 0.84 | NR1H2 (0.59) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL14687796 | 0.84 | NR1H2 (0.58) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL29631853 | 0.83 | HDAC2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL31651962 | 0.83 | TLR9 (0.50) | GPR119DDB1CRBN | |
| SCHEMBL31410407 | 0.82 | NR1H2 (0.57) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL31410394 | 0.82 | NR1H2 (0.57) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL16442376 | 0.82 | GPR119 (0.50) | GPR119RETDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |