Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.56 |
| ▸ | CKS1B | P61024 | 2/20 | 0.54 |
| ▸ | SKP1 | P63208 | 2/20 | 0.54 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395474 | 1.00 | GPR119 (0.56) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL25195768 | 0.88 | GPR119 (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL14614610 | 0.83 | CKS1B (0.59) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL25197136 | 0.83 | GPR119 (0.55) | GPR119 | |
| SCHEMBL2366254 | 0.81 | DDB1 (0.59) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL1995627 | 0.81 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL1873796 | 0.81 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL4724234 | 0.81 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL30376692 | 0.81 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL3294544 | 0.81 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |