SCHEMBL29030224

SCHEMBL29030224

CC1CC[Si](C)(CCCOCC2CO2)[Si](C)(C)O1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760116 0.75 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL29072300 0.73
SCHEMBL16661604 0.72 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13532301 0.72 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL18371651 0.72 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2066081 0.72 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2006386 0.72 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5355597 0.71 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL27047999 0.71 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL21301101 0.70 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117979899-A Sensor with varying stiffness 豪夫迈·罗氏有限公司 2024-05-03 CN disclosed
CN-117836618-A Opening formation in a film 豪夫迈·罗氏有限公司 2024-04-05 CN disclosed
CN-117597068-A Analyte sensor and method for producing an analyte sensor 豪夫迈·罗氏有限公司 2024-02-23 CN disclosed
CN-114316236-B High-temperature-resistant polycarbonate material and preparation method thereof 深圳市元创化工科技有限公司 2023-09-08 CN disclosed
CN-116528990-A Working electrode for analyte sensor 豪夫迈·罗氏有限公司 2023-08-01 CN disclosed
CN-116419710-A Flux limiting polymeric membranes 豪夫迈·罗氏有限公司 2023-07-11 CN disclosed
CN-115997028-A Analyte sensor and manufacture thereof 豪夫迈·罗氏有限公司 2023-04-21 CN disclosed
CN-115280142-A Method for preparing a working electrode comprising laser irradiation of a sensing material and corresponding analyte sensor 豪夫迈·罗氏有限公司 2022-11-01 CN disclosed