Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030480 | 1.00 | NLRP3 (0.40) | NLRP3EHMT2BTKJUNMAPK8 | |
| SCHEMBL25302366 | 0.94 | PIK3CD (0.41) | NLRP3EHMT2BTKJUNMAPK8 | |
| SCHEMBL25302362 | 0.94 | PIK3CD (0.41) | NLRP3EHMT2BTKJUNMAPK8 | |
| SCHEMBL25256084 | 0.91 | NLRP3 (0.42) | NLRP3EHMT2BTKPIK3CDKDM4E | |
| SCHEMBL30488527 | 0.91 | NLRP3 (0.42) | NLRP3EHMT2BTKPIK3CDKDM4E | |
| SCHEMBL25302706 | 0.91 | NLRP3 (0.42) | NLRP3EHMT2BTKPIK3CDKDM4E | |
| SCHEMBL31197253 | 0.89 | NLRP3 (0.39) | NLRP3EHMT2BTKCDK2PIK3CD | |
| SCHEMBL29030517 | 0.88 | NLRP3 (0.40) | NLRP3EHMT2BTKJUNMAPK8 | |
| SCHEMBL29030518 | 0.88 | NLRP3 (0.40) | NLRP3EHMT2BTKJUNMAPK8 | |
| SCHEMBL25296227 | 0.88 | NLRP3 (0.50) | NLRP3BTKCDK2ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |