Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488567 | 1.00 | PIM1 (0.36) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL29030515 | 1.00 | PIM1 (0.36) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL30488491 | 0.89 | PIM1 (0.35) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL29030550 | 0.89 | PIM1 (0.35) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL30488568 | 0.89 | PIM1 (0.35) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL29030552 | 0.89 | PIM1 (0.35) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL30488591 | 0.85 | USP30 (0.37) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL29030472 | 0.85 | USP30 (0.37) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL29030471 | 0.85 | USP30 (0.37) | PIM1PIM2USP30ALOX5APFEN1 | |
| SCHEMBL30893678 | 0.85 | NLRP3 (0.45) | PIM1PIM2USP30AHCYNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |