Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 19/20 | 0.67 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567304 | 1.00 | KHK (0.67) | KHKPDE10AHPGD | |
| SCHEMBL29030971 | 1.00 | KHK (0.67) | KHKPDE10AHPGD | |
| SCHEMBL29031022 | 0.88 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL29030995 | 0.88 | KHK (0.62) | KHKPDE10A | |
| SCHEMBL29031000 | 0.88 | KHK (0.62) | KHKPDE10A | |
| SCHEMBL29030937 | 0.87 | KHK (0.60) | KHKPDE10A | |
| SCHEMBL30567272 | 0.87 | KHK (0.60) | KHKPDE10A | |
| SCHEMBL29030941 | 0.87 | KHK (0.60) | KHKPDE10A | |
| SCHEMBL25245843 | 0.86 | KHK (0.66) | KHKPDE10A | |
| SCHEMBL25291509 | 0.86 | KHK (0.66) | KHKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |