Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 19/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030941 | 1.00 | KHK (0.60) | KHKPDE10AFFAR4 | |
| SCHEMBL29030937 | 1.00 | KHK (0.60) | KHKPDE10AFFAR4 | |
| SCHEMBL29438113 | 0.91 | KHK (0.61) | KHKPDE10A | |
| SCHEMBL29030971 | 0.87 | KHK (0.67) | KHKPDE10A | |
| SCHEMBL30567304 | 0.87 | KHK (0.67) | KHKPDE10A | |
| SCHEMBL29030977 | 0.87 | KHK (0.67) | KHKPDE10A | |
| SCHEMBL23592029 | 0.82 | KHK (0.64) | KHKPDE10A | |
| SCHEMBL30567252 | 0.82 | KHK (0.64) | KHKPDE10A | |
| SCHEMBL25245843 | 0.81 | KHK (0.66) | KHKPDE10A | |
| SCHEMBL25291509 | 0.81 | KHK (0.66) | KHKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |