SCHEMBL29032166

SCHEMBL29032166

CC(=O)NCCc1nccc2ccc(OC3CC3)cc12

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 18/20 0.60
MTNR1B P49286 14/20 0.51
HTR2C P28335 2/20 0.46
HTR2B P41595 1/20 0.46
ACACB O00763 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29032202 0.85 MTNR1A (0.69) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL29032206 0.84 MTNR1A (0.57) MTNR1AMTNR1BHTR2CHTR2BACACB
SCHEMBL30448723 0.83 MTNR1A (0.56) MTNR1AMTNR1BHTR2CHTR2BACACB
SCHEMBL29032185 0.83 MTNR1A (0.56) MTNR1AMTNR1BHTR2CHTR2BACACB
SCHEMBL29032157 0.80 MTNR1A (0.73) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL30449211 0.80 MTNR1A (0.73) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL29032165 0.79 MTNR1A (0.61) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL30449222 0.78 MTNR1A (0.72) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL29032218 0.76 MTNR1A (0.67) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL29032143 0.76 MTNR1A (0.67) MTNR1AMTNR1BHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116249691-B Bicyclic derivative regulator, preparation method and application thereof 上海翰森生物医药科技有限公司 2025-04-25 CN disclosed
CN-116249691-A Bicyclic derivative regulator, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-06-09 CN disclosed