Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534680 | 0.82 | IDO1 (0.43) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27713690 | 0.78 | TACR1 (0.35) | TACR1CYP3A4CYP2C9CYP2C19SLC6A2 | |
| SCHEMBL29155357 | 0.77 | SLC6A4 (0.39) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30702301 | 0.77 | SLC6A4 (0.39) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15120041 | 0.77 | TAAR1 (0.45) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL352619 | 0.76 | CALM1 (0.52) | — | |
| SCHEMBL27950266 | 0.76 | HSPA5 (0.58) | CYP3A4 | |
| SCHEMBL28231299 | 0.76 | HPGD (0.38) | TACR1CYP3A4CYP2C9CYP2C19SLC6A2 | |
| SCHEMBL21380597 | 0.75 | HSPA5 (0.46) | CYP3A4CYP2C9CYP2C19PSMD14COPS5 | |
| SCHEMBL28039804 | 0.74 | CALM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253731-B | Preparation method of indolizine compound | 宜春学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-117347518-A | Detection method for related substances of key starting materials of voathixetine | 山东京卫制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116253731-A | Preparation method of indolizine compound | 宜春学院 | 2023-06-13 | — | — | CN | disclosed |