Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | ABL1 | P00519 | 3/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | FER | P16591 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451514 | 0.93 | ABL1 (0.56) | MEN1KMT2ANPC1RAB9AABL1 | |
| SCHEMBL29032783 | 0.93 | ABL1 (0.56) | MEN1KMT2ANPC1RAB9AABL1 | |
| SCHEMBL29032788 | 0.88 | ABL1 (0.58) | ABL1HDAC6JAK2MAP4K4CHEK2 | |
| SCHEMBL29032719 | 0.87 | ABL1 (0.57) | ABL1HDAC6JAK2MAP4K4CHEK2 | |
| SCHEMBL30451175 | 0.87 | ABL1 (0.57) | ABL1HDAC6JAK2MAP4K4CHEK2 | |
| SCHEMBL29032765 | 0.86 | ABL1 (0.56) | NPC1RAB9AABL1SENP1HDAC6 | |
| SCHEMBL29032722 | 0.85 | ABL1 (0.54) | ABL1HDAC6JAK2MAP4K4CHEK2 | |
| SCHEMBL30450800 | 0.85 | ABL1 (0.54) | ABL1HDAC6JAK2MAP4K4CHEK2 | |
| SCHEMBL29032695 | 0.84 | ABL1 (0.54) | NPC1RAB9AABL1SENP1HDAC6 | |
| SCHEMBL30450521 | 0.84 | NPC1 (0.57) | NPC1RAB9AABL1SENP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | claimed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | claimed |
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |