SCHEMBL29033432

SCHEMBL29033432

O=C(O)c1occc1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.41
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 4/20 0.34
HSD17B10 Q99714 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
ESR1 P03372 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
MAPK1 P28482 1/20 0.33
ESR2 Q92731 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 2/20 0.32
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28381392 0.82 TTR (0.36) ACLYTDP1HSD17B10ALDH1A1CASP1
SCHEMBL6470461 0.77 NPSR1 (0.47) ACLYKMT2AALDH1A1POLBTSHR
SCHEMBL2040078 0.71
SCHEMBL27651919 0.71 TTR (0.32) ALDH1A1TSHRSMN1; SMN2
SCHEMBL3697434 0.70 TTR (0.31) HSD17B10TSHRSMN1; SMN2HPGD
SCHEMBL29155974 0.70 TTR (0.31) TSHRSMN1; SMN2
SCHEMBL29443136 0.70 TTR (0.31) TSHRSMN1; SMN2
SCHEMBL1781537 0.69
SCHEMBL28257547 0.69 L3MBTL1 (0.45) ACLYKMT2ATDP1HSD17B10ALDH1A1
SCHEMBL38507 0.69 L3MBTL1 (0.45) ACLYKMT2ATDP1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114615890-B Herbicidal mixtures comprising aminopyridine and quinic acid 安道麦阿甘有限公司 2024-02-13 CN disclosed
CN-113163750-B Aqueous solutions of poorly soluble pesticides using polyalkoxylated alcohols 陶氏环球技术有限责任公司 2023-09-29 CN disclosed
CN-116390920-A Aromatic spirocyclic amide derivatives for the treatment and prevention of hepatitis b virus infection 豪夫迈·罗氏有限公司 2023-07-04 CN disclosed
CN-114409676-A Preparation method of 7-ACF 河南立诺制药有限公司 2022-04-29 CN disclosed