Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787084 | 0.91 | PRKCI (0.51) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| SCHEMBL5891427 | 0.80 | PRKCI (0.47) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| SCHEMBL2096438 | 0.74 | PRKCI (0.47) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| Hydrochloric Acid SCHEMBL3807554 | 0.73 | ALDH1A1 (0.44) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| SCHEMBL11232049 | 0.72 | PRKCI (0.43) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| SCHEMBL15260619 | 0.72 | PARP1 (0.43) | PRKCIKDM4ELMNACYP1A2BLM | |
| SCHEMBL1710995 | 0.71 | NPC1 (0.45) | KDM4ECYP1A2BLMTDP1JAK2 | |
| SCHEMBL404747 | 0.71 | PRKCI (0.56) | PRKCIKDM4ELMNAHIF1ACCR1 | |
| SCHEMBL25434885 | 0.70 | AURKA (0.44) | KDM4ELMNAHIF1ACYP1A2BLM | |
| SCHEMBL25434324 | 0.70 | JAK2 (0.37) | PRKCIBTKCHEK1JAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178345-A | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178345-A | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178345-A | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |