Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 19/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.67 |
| ▸ | ATR | Q13535 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512915 | 0.83 | FYN (1.00) | FYNPIK3CAATR | |
| SCHEMBL30521838 | 0.83 | FYN (1.00) | FYNPIK3CAATR | |
| SCHEMBL1202851 | 0.82 | FYN (0.62) | FYNPIK3CAATR | |
| SCHEMBL14024005 | 0.81 | FYN (0.76) | FYNPIK3CAATR | |
| SCHEMBL3512864 | 0.80 | PIK3CA (1.00) | FYNPIK3CAATR | |
| SCHEMBL3515271 | 0.80 | FYN (0.74) | FYNPIK3CAATR | |
| SCHEMBL18613675 | 0.79 | FYN (1.00) | FYN | |
| SCHEMBL16330948 | 0.78 | FYN (1.00) | FYNPIK3CAATR | |
| SCHEMBL3514483 | 0.78 | FYN (0.83) | FYNPIK3CAATR | |
| SCHEMBL20485736 | 0.78 | FYN (1.00) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217601-A1 | IMIDAZOPYRIDAZINES FOR USE AS PROTEIN KINASE INHIBITORS | Centro Nacional de Investigaciones Oncológicas (CNIO) (ES) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009060197-A1 | IMIDAZOPYRIDAZINES FOR USE AS PROTEIN KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2009-05-14 | — | — | WO | disclosed |