SCHEMBL29033930

SCHEMBL29033930

O=C(Cl)CCSc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C19 P33261 1/20 0.59
MAPK1 P28482 1/20 0.56
RAB9A P51151 8/20 0.54
NPC1 O15118 6/20 0.54
SMN1; SMN2 Q16637 6/20 0.54
FFAR1 O14842 1/20 0.52
HPGD P15428 3/20 0.50
LMNA P02545 2/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
TSHR P16473 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160357 0.88 ALDH1A1 (0.72) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL2726129 0.86 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL7367100 0.85 HDAC1 (0.66) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL1930794 0.83 ALDH1A1 (0.77) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL11605711 0.80 HSP90AA1 (0.58) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL20577869 0.80 HPGD (0.58) ALDH1A1RAB9ANPC1SMN1; SMN2HPGD
SCHEMBL953807 0.79 CYP1A2 (0.65) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL6912718 0.79 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL953806 0.79 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL14668806 0.79 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116034126-A Holographic recording material and preparation method thereof 科罗拉多大学评议会公司 2023-04-28 CN disclosed