Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL29034262 | 0.87 | NFE2L2 (0.53) | NFE2L2KDM4ELMNAHPGDCA12 | |
| Acrylic Acid SCHEMBL29034269 | 0.85 | NFE2L2 (0.51) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL28556152 | 0.84 | NFE2L2 (0.50) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL28714121 | 0.82 | NFE2L2 (0.53) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL28767207 | 0.80 | NFE2L2 (0.46) | NFE2L2KDM4ELMNAHPGDCA12 | |
| Formaldehyde SCHEMBL28092618 | 0.80 | SMN1; SMN2 (0.54) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL28085824 | 0.79 | NFE2L2 (0.50) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL28256474 | 0.78 | NFE2L2 (0.50) | NFE2L2KDM4ELMNAHPGDCA12 | |
| SCHEMBL27900427 | 0.78 | SMN1; SMN2 (0.48) | NFE2L2KDM4ELMNAHPGDCA12 | |
| Formic Acid SCHEMBL28191601 | 0.78 | NFE2L2 (0.55) | NFE2L2KDM4ELMNAHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702436-B | Application of piperlonguminine compound in preparation of medicines for treating schistosomiasis japonica and pharmaceutical composition | 赣南师范大学 | 2023-07-14 | — | — | CN | disclosed |