Carbamic Acid

Carbamic Acid

SCHEMBL29034276

C=C(C)C.NC(=O)O.NC(=O)OCCI

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CHRM5 P08912 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
HTR1A P08908 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
CHRNA7 P36544 1/20 0.42
ALOX15 P16050 1/20 0.39
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113903 0.84
SCHEMBL30036148 0.72 ALOX15 (0.37) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL28243014 0.71
SCHEMBL491448 0.71
SCHEMBL28917359 0.71 TSHR (0.41) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL4699293 0.71 TSHR (0.41) LMNACHRM2CHRM4CHRM5CHRM1
Methacrylic Acid SCHEMBL28026130 0.71 TSHR (0.42) LMNACHRM2CHRM4CHRM5CHRM1
Methacrylic Acid SCHEMBL17105847 0.71 ALOX15 (0.44) LMNACHRM2CHRM4CHRM5CHRM1
Carbamic Acid SCHEMBL4361098 0.71 TDP1 (0.60) LMNATSHRALOX15TDP1HSD17B10
Carbamic Acid SCHEMBL27789804 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384517-B Heteroaryl compounds and uses thereof 新旭生技股份有限公司 2023-07-14 CN disclosed