SCHEMBL29034282

SCHEMBL29034282

C=C(C)C1CCC2=CCCC(C)(C)C2C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
ALOX15 P16050 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.36
TRPA1 O75762 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2C19 P33261 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22854611 0.76 HDAC6 (0.31)
SCHEMBL2724484 0.74 CYP2C19 (0.42) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL17633710 0.70 LMNA (0.42) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL567659 0.70 HDAC6 (0.47) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL17627664 0.70 HDAC6 (0.47) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL30105630 0.70 HDAC6 (0.47) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL3438652 0.70 HDAC6 (0.47) LMNAALOX15CYP1B1ALDH1A1TSHR
SCHEMBL10934411 0.64
SCHEMBL18392042 0.63 CA1 (0.33) ALOX15CYP1B1ALDH1A1CA1CA2
SCHEMBL19924541 0.62 ESR2 (0.33) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044574-B Vanilla alkene synthase mutant and application thereof in synthesizing valansia alkene in yeast 华东理工大学 2023-07-14 CN disclosed