Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 11/20 | 0.60 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855794 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL855400 | 0.95 | NOS2 (0.60) | NOS2NOS3NOS1LMNA | |
| SCHEMBL20742601 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL21712013 | 0.80 | — | — | |
| SCHEMBL9705753 | 0.76 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| Cyclopropanecarboximidamide SCHEMBL1221622 | 0.76 | — | — | |
| SCHEMBL9705757 | 0.76 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| Cyclopropanecarboximidamide SCHEMBL25215941 | 0.74 | — | — | |
| Cyclopropanecarboximidamide SCHEMBL275450 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9292761 | 0.74 | NOS2 (0.93) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396274-A | Substituted bipyridone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-07-07 | — | — | CN | disclosed |