Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 12/20 | 0.72 |
| ▸ | ULK1 | O75385 | 2/20 | 0.69 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | INSR | P06213 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 1/20 | 0.67 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.67 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 2/20 | 0.65 |
| ▸ | MET | P08581 | 1/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144557 | 0.90 | ULK1 (0.81) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL2637033 | 0.87 | PTK2 (0.79) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL2029934 | 0.83 | PTK2 (1.00) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL1038459 | 0.82 | ALK (0.63) | PTK2MAPK9MAPK10INSRMET | |
| SCHEMBL17547514 | 0.82 | ULK1 (1.00) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL12311805 | 0.82 | ULK1 (0.82) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL2593046 | 0.81 | ALK (0.77) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL25668076 | 0.81 | PTK2 (0.84) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL2029937 | 0.81 | PTK2 (0.66) | PTK2ULK1MAPK8MAPK9MAPK10 | |
| SCHEMBL17547487 | 0.80 | ULK1 (0.83) | PTK2ULK1MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425735-B | 2, 4-Diphenylamine pyrimidine derivative, and preparation method and application thereof | 中南大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-116425735-A | 2, 4-diphenylamine pyrimidine derivative, and preparation method and application thereof | 中南大学 | 2023-07-14 | — | — | CN | disclosed |