SCHEMBL29034879

SCHEMBL29034879

COc1ccc(OP(=O)(O)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.61
CA2 P00918 2/20 0.61
CA5A P35218 2/20 0.61
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA5B Q9Y2D0 1/20 0.61
PKM P14618 1/20 0.56
HTT P42858 1/20 0.56
ACP3 P15309 1/20 0.54
HPGD P15428 1/20 0.53
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SRC P12931 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618715 0.90 CA1 (0.49) CA4CA2CA5ACA12CA1
SCHEMBL20819121 0.90 CA2 (0.71) CA4CA2CA5ACA12CA1
SCHEMBL752987 0.86 CA2 (0.66) CA4CA2CA5ACA12CA1
Benzene SCHEMBL28297820 0.86 CA2 (0.66) CA4CA2CA5ACA12CA1
SCHEMBL29034894 0.85 CA2 (0.61) CA4CA2CA5ACA12CA1
SCHEMBL672612 0.84 CA2 (0.64) CA4CA2CA5ACA12CA1
SCHEMBL639056 0.84 CA2 (0.64) CA4CA2CA5ACA12CA1
SCHEMBL673830 0.84 CA2 (0.64) CA4CA2CA5ACA12CA1
SCHEMBL9584229 0.84 CA2 (0.64) CA4CA2CA5ACA12CA1
SCHEMBL3963455 0.84 CA2 (0.64) CA4CA2CA5ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425794-A Aryl phosphonate compound and preparation method thereof 烟台大学 2023-07-14 CN claimed