SCHEMBL29035666

SCHEMBL29035666

C=CC(=O)OCCCCCCC(C)O[SiH3]

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.61
ALDH1A1 P00352 5/20 0.61
CYP3A4 P08684 3/20 0.61
HPGD P15428 2/20 0.51
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
HCAR2 Q8TDS4 3/20 0.36
ATM Q13315 1/20 0.34
FAAH O00519 1/20 0.33
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445636 0.98 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7525915 0.93 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
Propene SCHEMBL28139307 0.90 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
Propene SCHEMBL28212160 0.88 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29845548 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30190367 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31636154 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10867522 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL813080 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6731836 0.83 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716491-B Method for manufacturing field effect transistor and method for manufacturing wireless communication device 东丽株式会社 2023-06-09 CN disclosed