Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL28139307 | 0.97 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4445636 | 0.95 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Propene SCHEMBL28212160 | 0.94 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29035666 | 0.93 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3241213 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8565036 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27134193 | 0.84 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8899037 | 0.83 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL650621 | 0.82 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL6520468 | 0.81 | ATM (0.43) | TSHRALDH1A1CYP3A4HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449413-B1 | Polymers | ICI PLC (GB) | 1995-12-20 | — | — | EP | claimed |
| US-5274064-A | An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | claimed |
| EP-0449413-A1 | Polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-02 | — | — | EP | claimed |
| JP-54144494-A | — | — | None | — | — | JP | disclosed |
| CN-105142644-A | Onapristone polymorphic forms and methods of use | ARNO THERAPEUTICS | 2015-12-09 | — | — | CN | disclosed |
| US-20020016269-A1 | Particle perfume delivery system | THE PROCTER & GAMBLE CO. | 2002-02-07 | — | — | US | disclosed |
| WO-2002004586-A1 | A PARTICLE PERFUME DELIVERY SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2000068275-A1 | NON-SYMMETRICAL FREE RADICAL INITIATORS AND PROCESS FOR USE THEREWITH | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-16 | — | — | WO | disclosed |
| EP-0449413-B1 | Polymers | ICI PLC (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5274064-A | An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | disclosed |
| EP-0449413-A1 | Polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-02 | — | — | EP | disclosed |
| JP-S54144494-A | HEAT-CURABLE ADHESIVE COMPOSITION HAVING IMPROVED PLATING PROPERTY | HITACHI LTD | 1979-11-10 | — | — | JP | disclosed |