Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035734 | 0.83 | GAA (0.50) | TDP1CDK1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL29035714 | 0.83 | KDM4E (0.41) | EGFRNOX4TDP1CDK1SMN1; SMN2 | |
| SCHEMBL2114067 | 0.78 | POLB (0.51) | CDK1SMN1; SMN2LMNAKDM4EGAA | |
| SCHEMBL23717441 | 0.77 | ALDH1A1 (0.59) | EGFRNOX4TDP1CDK1SMN1; SMN2 | |
| SCHEMBL21900515 | 0.77 | KMT2A (0.58) | EGFRNOX4TDP1SMN1; SMN2LMNA | |
| SCHEMBL1914436 | 0.76 | PTPN11 (0.40) | LMNAMEN1KMT2AKDM4EGAA | |
| SCHEMBL13277325 | 0.75 | ABL1 (0.54) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL17883969 | 0.75 | IDH1 (0.38) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL19583419 | 0.75 | NR4A2 (0.48) | SMN1; SMN2GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL15763208 | 0.75 | SMN1; SMN2 (0.64) | EGFRNOX4TDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |