SCHEMBL29035792

SCHEMBL29035792

CC(C)(C)c1cccc(C(C)(C)C)c1.O=C(OO)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
MAPT P10636 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ACHE P22303 3/20 0.51
RXRA P19793 2/20 0.49
RXRB P28702 2/20 0.49
TNF P01375 1/20 0.48
KLF5 Q13887 1/20 0.48
NOD1 Q9Y239 1/20 0.48
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KCNK9 Q9NPC2 1/20 0.46
ESRRG P62508 1/20 0.44
LMNA P02545 2/20 0.44
F2 P00734 1/20 0.44
HDAC8 Q9BY41 2/20 0.43
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylbenzene SCHEMBL28557232 0.91 MAPT (0.64) TDP1MAPTL3MBTL1ACHETNF
SCHEMBL30386758 0.89 ACHE (0.59) TDP1MAPTL3MBTL1ACHERXRA
SCHEMBL669361 0.89 ACHE (0.59) TDP1MAPTL3MBTL1ACHERXRA
SCHEMBL5583927 0.83 TDP1 (0.53) TDP1MAPTL3MBTL1ACHERXRA
SCHEMBL27332603 0.83 ACHE (0.56) TDP1MAPTL3MBTL1ACHERXRA
Tert-Butanol SCHEMBL28695545 0.81 TDP1 (0.57) TDP1MAPTL3MBTL1TNFKLF5
Chloromethane SCHEMBL27484052 0.81 TSHR (0.60) TDP1MAPTL3MBTL1TSHRALDH1A1
SCHEMBL11072811 0.81 MAPK1 (0.61) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL13110206 0.80 MAPT (0.69) TDP1MAPTL3MBTL1ACHEALDH1A1
Tert-Butyl Hydroperoxide SCHEMBL4202826 0.80 TDP1 (0.60) TDP1MAPTL3MBTL1TNFKLF5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527442-B System and method for customizing photochromic articles 光学转变有限公司 2023-07-21 CN disclosed