Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149876 | 1.00 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL19196204 | 0.90 | TP53 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL13921726 | 0.89 | L3MBTL1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL19195922 | 0.87 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2339443 | 0.85 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1NR1H2 | |
| SCHEMBL29035849 | 0.84 | NR1H2 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17336613 | 0.83 | AHR (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL13921711 | 0.82 | NR1H2 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL13936045 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1NR1H2 | |
| SCHEMBL13936046 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115532318-B | MOF-supported metal catalyst and preparation method and application thereof | 江南大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115532318-A | MOF-loaded metal catalyst and preparation method and application thereof | 江南大学 | 2022-12-30 | — | — | CN | disclosed |