Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL27910487 | 0.86 | — | — | |
| Iodide SCHEMBL568698 | 0.86 | — | — | |
| Bromide SCHEMBL4541742 | 0.86 | — | — | |
| SCHEMBL10550807 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL394292 | 0.76 | — | — | |
| SCHEMBL6268658 | 0.76 | — | — | |
| SCHEMBL1229530 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27262811 | 0.67 | — | — | |
| Bromide SCHEMBL395996 | 0.63 | — | — | |
| SCHEMBL9001246 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037016-A | Main catalyst component for olefin polymerization, preparation method and application | 中国石油天然气股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-118894769-A | Preparation method of dydrogesterone and key intermediate thereof | 中国科学院天津工业生物技术研究所 | 2024-11-05 | — | — | CN | claimed |
| CN-116410363-A | Catalyst, preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-108368121-B | Process for the preparation of imidazo [1,2-a ] pyrrolo [2,3-e ] pyrazines | 艾伯维公司（US） | 2023-01-13 | — | — | CN | claimed |
| US-20210363149-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | ABBVIE INC (US) | 2021-11-25 | — | — | US | claimed |
| CN-111995883-B | Preparation method of metal oxide/hollow microsphere composite filler | 中国石油化工股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-111995883-A | Preparation method of metal oxide/hollow microsphere composite filler | 中国石油化工股份有限公司 | 2020-11-27 | — | — | CN | claimed |
| EP-3362455-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | AbbVie Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| US-20170129902-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-alpha]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-05-11 | — | — | US | claimed |
| WO-2017066775-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | ABBVIE INC. (US) | 2017-04-20 | — | — | WO | claimed |
| CN-101514193-B | Synthesis of furan substituted dioxo cyclobutene | MERCK SHARP & DOHME | 2012-12-19 | — | — | CN | claimed |
| CN-101514193-A | Synthesis of 2-hydroxy-n,n-dimethyl-3-[[2-[1(r)-(5-methyl-2-furanyl) propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]benzamide | SCHERING CORP (US) | 2009-08-26 | — | — | CN | claimed |
| CN-100448860-C | Synthesis of 2-hydroxy-N, N-dimethyl-3- [ [ 2- [ [1 - (5-methyl-2-furyl) propyl ] amino ] -3, 4-dioxo-1-cyclobuten-1-yl ] amino ] benzamide | SCHERING CORP (US) | 2009-01-07 | — | — | CN | claimed |
| CN-1805947-A | Synthesis of 2-hydroxy-N, N-dimethyl-3- [ [ 2- [ [1 - (5-methyl-2-furyl) propyl ] amino ] -3, 4-dioxo-1-cyclobuten-1-yl ] amino ] benzamide | SCHERING CORP (US) | 2006-07-19 | — | — | CN | claimed |
| CN-122037016-A | Main catalyst component for olefin polymerization, preparation method and application | 中国石油天然气股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| US-12398151-B2 | Sumo inhibitor compounds and uses thereof | Suvalent Therapeutics, Inc. (US) | 2025-08-26 | — | — | US | disclosed |
| US-4238355-A | A TITANIUM COMPOUND, A ZINC COMPOUND, AN ORGANOMAGNESIUM COMPOUND, AND A HALIDE SOURCE | THE DOW CHEMICAL COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4100183-A | Process for preparing cuprous aluminum tetrahalide complexing agents | THE DOW CHEMICAL COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4022808-A | ZINC-ALUMINUM-TITANIUM-TIN-IRON OR GROUP 5A AS CATALYSTS | NIPPON SODA COMPANY LIMITED (JA) | 1977-05-10 | — | — | US | disclosed |