Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24208929 | 0.84 | MAPT (0.62) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL31596346 | 0.83 | MAPT (0.59) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL27875662 | 0.82 | RAB9A (0.55) | MAPTRAB9AGAAPRKCZSMN1; SMN2 | |
| SCHEMBL29743169 | 0.82 | RAB9A (0.55) | MAPTRAB9AGAAPRKCZSMN1; SMN2 | |
| SCHEMBL26756135 | 0.77 | AR (0.57) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL5464409 | 0.76 | MAPT (0.52) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL11395126 | 0.76 | MAPT (0.59) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL7012400 | 0.76 | MAPT (0.47) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL4249297 | 0.75 | GRM6 (0.70) | MAPTRAB9AGAAPRKCZAR | |
| SCHEMBL28362521 | 0.75 | KCNJ1 (0.64) | MAPTRAB9AGAAPRKCZAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790189-B | Preparation method of intermediate of Rayleigh Lu Geli | 海化生命(厦门)科技有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-114790189-A | Preparation method of Ruugeli intermediate | 海化生命(厦门)科技有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-114790189-B | Preparation method of intermediate of Rayleigh Lu Geli | 海化生命(厦门)科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114790189-B | Preparation method of intermediate of Rayleigh Lu Geli | 海化生命(厦门)科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114790189-A | Preparation method of Ruugeli intermediate | 海化生命(厦门)科技有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114790189-A | Preparation method of Ruugeli intermediate | 海化生命(厦门)科技有限公司 | 2022-07-26 | — | — | CN | disclosed |