Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCL3 | P20749 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035992 | 0.87 | NAAA (0.52) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL29036058 | 0.85 | CDK1 (0.53) | NAAAALDH1A1HTT | |
| SCHEMBL13385672 | 0.80 | POLB (0.61) | NAAANAMPTALDH1A1HPGDTSHR | |
| SCHEMBL15127579 | 0.78 | NAAA (0.69) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL25794246 | 0.77 | NAAA (0.63) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL29036061 | 0.77 | NAAA (0.51) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL823552 | 0.76 | NAAA (0.84) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| Salcaprozic Acid SCHEMBL29036079 | 0.75 | NAAA (0.54) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL14271965 | 0.75 | NAAA (0.68) | NAAANAMPTALOX5NPC1ALDH1A1 | |
| SCHEMBL31298077 | 0.74 | KMT2A (0.67) | ALDH1A1HPGDBCL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | disclosed |