Hydroquinone

Hydroquinone

SCHEMBL29036348

CC(=O)O.Cc1cccc2ccccc12.Oc1ccc(O)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.63
ALDH1A1 P00352 2/20 0.63
DEGS1 O15121 1/20 0.46
CYP1A2 P05177 5/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.42
LDHA P00338 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GFER P55789 1/20 0.41
TNKS O95271 1/20 0.41
PARP1 P09874 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
CDC25B P30305 1/20 0.41
PLK1 P53350 1/20 0.41
POLB P06746 1/20 0.40
FABP3 P05413 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL31412758 0.92 ALDH1A1 (0.74) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Acetic Acid SCHEMBL1961579 0.92 ALDH1A1 (0.74) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Acetic Acid SCHEMBL28004587 0.90 ALDH1A1 (0.71) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Hydroquinone SCHEMBL28352613 0.90 CYP2A6 (0.77) CYP2A6ALDH1A1DEGS1CYP1A2HPGD
Phenol SCHEMBL27876144 0.88 CYP2A6 (0.74) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Phenol SCHEMBL28193106 0.86 CYP2A6 (0.71) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Acetone SCHEMBL27948247 0.86 CYP2A6 (0.77) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Bicarbonate SCHEMBL809258 0.86 CYP2A6 (0.77) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Butanedione SCHEMBL27716374 0.84 ALDH1A1 (0.74) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10
Carbamic Acid SCHEMBL28454155 0.82 ALDH1A1 (0.71) CYP2A6ALDH1A1CYP1A2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114128794-B Feed for termite animals, preparation method thereof and method for raising termite animals by feed 广东长隆集团有限公司 2024-03-26 CN disclosed
CN-116462588-A Preparation method of vitamin K4 浙江新和成药业有限公司 2023-07-21 CN disclosed