Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331541 | 0.78 | RIPK1 (0.44) | AXLTYRO3MERTKRIPK1 | |
| SCHEMBL29037136 | 0.78 | AXL (0.41) | AXLTYRO3MERTKRIPK1ALOX5AP | |
| SCHEMBL22470600 | 0.72 | MCHR1 (0.44) | AXLTYRO3MERTKRIPK1SCN9A | |
| SCHEMBL30468374 | 0.71 | HTR2C (0.38) | ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL22370975 | 0.71 | HTR2C (0.38) | ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL24180121 | 0.71 | ALOX5AP (0.34) | RIPK1ALOX5APFEN1 | |
| SCHEMBL22391549 | 0.71 | RIPK1 (0.48) | RIPK1ALOX5APFEN1SCN9AFFAR4 | |
| SCHEMBL9230318 | 0.71 | PARP10 (0.45) | SCN9AFFAR4PARP15PARP10 | |
| SCHEMBL27806917 | 0.71 | IDO1 (0.46) | — | |
| SCHEMBL28331563 | 0.71 | FFAR4 (0.34) | RIPK1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566103-B | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111566103-A | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2020-08-21 | — | — | CN | disclosed |