SCHEMBL29037430

SCHEMBL29037430

C=CC(=O)NC(=O)N[C@@H](C)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.32
FGFR4 P22455 1/20 0.32
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373316 0.84 TSHR (0.60) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL8373317 0.84 TSHR (0.60) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL28385316 0.73 TDP1 (0.36) TDP1
SCHEMBL2929027 0.71 TSHR (0.43) TSHRALDH1A1MAPK1TDP1
SCHEMBL259594 0.71 TSHR (0.48) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL28390453 0.71 TSHR (0.43) TSHRALDH1A1MAPK1TDP1
SCHEMBL28390454 0.71 TSHR (0.43) TSHRALDH1A1MAPK1TDP1
SCHEMBL11593070 0.70 TSHR (0.44) TSHR
SCHEMBL7046781 0.70 ALDH1A1 (0.42) TSHRALDH1A1MAPK1
Urea SCHEMBL27709911 0.69 ALDH1A1 (0.50) TSHRALDH1A1FGFR4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118649271-A Janus asymmetric moisture-conducting dressing with wound surface energizing effect and preparation method thereof 北京谱愈医疗科技有限公司 2024-09-17 CN claimed
CN-116641232-B Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2024-08-06 CN claimed
CN-116641232-A Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2023-08-25 CN claimed
CN-118649271-A Janus asymmetric moisture-conducting dressing with wound surface energizing effect and preparation method thereof 北京谱愈医疗科技有限公司 2024-09-17 CN disclosed
CN-116641232-B Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2024-08-06 CN disclosed
CN-116641232-B Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2024-08-06 CN disclosed
CN-116641232-A Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2023-08-25 CN disclosed
CN-116641232-A Dynamic temperature and humidity management fabric based on pore response and preparation method thereof 东华大学 2023-08-25 CN disclosed
CN-112726203-B Temperature-adaptive humidity-control temperature-regulating double-layer knitted fabric and preparation method thereof 深圳大学 2023-07-25 CN disclosed