Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037844 | 1.00 | HIF1A (0.47) | HIF1AHPGDLMNAGAAL3MBTL1 | |
| SCHEMBL30504782 | 0.98 | HIF1A (0.46) | HIF1AHPGDLMNAGAAL3MBTL1 | |
| SCHEMBL29037904 | 0.98 | HIF1A (0.46) | HIF1AHPGDLMNAGAAL3MBTL1 | |
| SCHEMBL7457790 | 0.86 | HIF1A (0.46) | HIF1AHPGDLMNAALDH1A1CYP2C9 | |
| SCHEMBL3129216 | 0.86 | HIF1A (0.46) | HIF1AHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL25389981 | 0.86 | HIF1A (0.52) | HIF1AHPGDLMNATP53ALDH1A1 | |
| SCHEMBL10433828 | 0.86 | HIF1A (0.45) | HIF1AHPGDLMNAGAAL3MBTL1 | |
| SCHEMBL3129211 | 0.86 | HIF1A (0.46) | HIF1AHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8078567 | 0.86 | HIF1A (0.45) | HIF1AHPGDLMNAGAAL3MBTL1 | |
| SCHEMBL3459416 | 0.86 | HIF1A (0.46) | HIF1AHPGDLMNAALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462650-A | Preparation method of 3-ketone-4- (methoxyimino) isochroman | 河北诚信集团有限公司 | 2023-07-21 | — | — | CN | disclosed |