SCHEMBL10433828

SCHEMBL10433828

CO/N=C(\C(N)=O)c1ccccc1CO

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.45
L3MBTL1 Q9Y468 3/20 0.40
LMNA P02545 3/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 2/20 0.39
TP53 P04637 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
PARP1 P09874 1/20 0.36
PKM P14618 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8078567 1.00 HIF1A (0.45) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL7913279 1.00 HIF1A (0.45) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL6156649 0.86 HIF1A (0.44) HIF1AL3MBTL1LMNAGAANPC1
SCHEMBL6227751 0.86 HIF1A (0.44) HIF1AL3MBTL1LMNAGAANPC1
SCHEMBL29037844 0.86 HIF1A (0.47) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL29037847 0.86 HIF1A (0.47) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL13823672 0.84 HIF1A (0.61) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL29037904 0.84 HIF1A (0.46) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL30504782 0.84 HIF1A (0.46) HIF1AL3MBTL1LMNAGAAHPGD
SCHEMBL27390096 0.84 HIF1A (0.43) HIF1AL3MBTL1LMNANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed